In pharmacology, bioavailability (BA) is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. By definition, when a medication is administered intravenously, its bioavailability is 100%. However, when a medication is administered via other routes (such as orally), its bioavailability generally decreases (due to incomplete absorption and first-pass metabolism) or may vary from patient to patient. Bioavailability is one of the essential tools in pharmacokinetics, as bioavailability must be considered when calculating dosages for non-intravenous routes of administration.
For dietary supplements, herbs and other nutrients in which the route of administration is nearly always oral, bioavailability generally designates simply the quantity or fraction of the ingested dose that is absorbed.
Fotos' first self-titled album was released through Labels (a Sublabel of EMI) on 29 September 2006. Fotos can be characterised as British-inspired indie rock in connection with German lyrics.
In summer 2007, the band played at the German Hurricane Festival and Southside Festival as well as at the Austrian FM4 Frequency Festival. Following the release of their second album Nach dem Goldrausch on 28 March 2008, the band went on tour in Germanyand Austria, and played several gigs at festivals in China. They played recently at German music festival organised by Max Mueller Bhavan in Pune, India and also at Delhi Public School Bangalore South where they were opened by the school's rock band "Velocity".
In 2008, the band's song "Fotos" was used as a Channel 4 "Try Life in Another Language" advert. In February 2009, Fotos represented the state of Lower Saxony at the Bundesvision Song Contest in Potsdam with their song "Du fehlst mir", ending on position No.15.